Contract Manufacturing

Product transfers can be difficult. With us, yours will be handled with care by a dedicated team of interdisciplinary specialists. Whether we have developed a formulation for you or you bring a semi-final or final formulation, we will put the right team together to answer your needs.

Contract Manufacturing with AdhexPharma

cGMP compliant with FDA and EMA standards

Worldwide Services

Highly potent APIs, Narcotics and Hormones

Product transfer and product launch

Your formulation comes from your own development, an external development partner or a manufacturer? Our specialists will be by your side, evaluating the formulation, visiting third-party actors and working together with them to transfer your formulation, analytical methods and manufacturing process to our equipment. Headed by experts in late stage development and registration, our team uses cGMP-compliant internal procedures to ensure compliance with governmental regulations.

Our product launch team will work closely with your experts to finalize product artwork for secondary packaging and commit to manufacturing launch batches within the agreed schedule. With vast experience in handling a high number of SKUs for each product, we offer exceptional flexibility when it comes to dosage strengths, pack sizes, and the number of target countries.

“AdhexPharma has invested several million euros in its production site to support a double digit growth. Our goal is to launch a new product with our customers every 18 months.”
Bruno Loiseau
Bruno Loiseau

Managing Director

Industrial equipment

AdhexPharma is equipped with high-performance industrial equipment for the contract production of patches and oral films. As a CDMO (Contract Development and Manufacturing Organization), the company handles the entire supply chain, including purchasing, mixing, manufacturing, packaging, and storage.

AdhexPharma is committed to the highest standards of quality, safety, and environmental protection.

The company guarantees its customers a level of service that meets their requirements.

  • Mixing: API and excipients in tanks ranging from 5 to 300 kg
  • Manufacturing: 5 lines, continuously controlled
  • Packaging: Multiple formats with maximum flexibility, from small to large series
  • Storage: 2000 m² capacity in pharmaceutical area
Industrial Equipment

Quality & Regulatory

AdhexPharma operates with the conviction that reliable quality is the key to success and the condition for sustainability. In order to maintain its commitment to quality over time, the company has the means to constantly verify the integrity of processes, data and products.

AdhexPharma operates a comprehensive, integrated quality system based on regulatory requirements, customer specifications and CDMO best practices. The quality system follows the guidelines of the current Good Manufacturing Practices (GMP or cGMP) and complies with the following standards:

  • EU GMP-ANSM & BfArM (French & German Authorities)
  • US cGMP—Food and Drug Administration (FDA)
  • 21 CFR 210, 211, 820
  • 21 CFR part 11
  • ISO 13485 (2016)
  • Release of batches by a Qualified Person (QP)

Since September 2020, AdhexPharma has been ISO 13485 certified, which ensures that its services meet customers' needs through an effective medical device quality management system.

Quality & Regulatory AdhexPharma

Our 5 steps of Contract Manufacturing

Step 1

Weighing & blending

Raw materials (API and excipients) are individually weighed and incorporated in a mixing vessel to obtain a homogeneous mixture.

1 Weighing and Blending
Step 1
Step 2

Coating & drying

The blended mixture is then pumped onto a process liner to create a smooth and consistent film. It's then run through several ovens to dry and is finally wound into a large roll, known as a "Jumbo roll" or "Mother roll". 

2 Coating and Drying
Step 2
Step 3


The jumbo roll is cut into smaller, more manageable rolls using a machine with blades or knives. It ensures consistent size and quality, making it easier to handle and package the final patches.

3 Slitting
Step 3
Step 4

Converting & primary packaging

The slitted daughter rolls are converted into patches or films, and are then brought into a primary package.

4 Converting and Primary Packaging
Step 4
Step 5

Secondary packaging

The pouches are then brought into secondary packaging.

5 Secondary Packaging
Step 5

Learn more about our manufacturing process

Our video will show you everything you need to know about the manufacturing steps of patches and oral films at AdhexPharma. 

Watch the video

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