10 Key questions about oral films: What you should know

Oral films are thin, flexible dosage forms that offer an effective and convenient approach to drug delivery. Depending on the product, they are placed on the tongue, under the tongue, or against the inside of the cheek, where they rapidly dissolve and release the Active Pharmaceutical Ingredient (API). Some medicines are absorbed directly through the oral mucosa, while others are swallowed with saliva and absorbed through the gastrointestinal tract.

They provide a convenient alternative to conventional tablets or capsules, particularly for patients who have difficulty swallowing, and can help improve treatment adherence. Oral films also enable precise dosing and, for certain medicines, a faster onset of action through absorption via the oral mucosa. When used according to the patient information leaflet and healthcare professional recommendations, they provide a safe and effective treatment option.

Here are 10 key questions to help you better understand how oral films work and how to use them properly.

1. How do I use an oral film correctly?
Always wash and dry your hands before handling the film. Open the individual sachet carefully, remove the film just before use and place it exactly as directed in the patient information leaflet (on the tongue, under the tongue, or inside the cheek, depending on the product). Allow the film to dissolve completely without chewing or swallowing it unless otherwise instructed. 

2. Do I need water to take an oral film?
In most cases, oral films are designed to be taken without water, making them a convenient option for patients who have difficulty swallowing tablets. Simply place the film as directed and allow it to dissolve naturally. However, always follow the instructions provided with your specific medicine, as recommendations may vary.

3. Can I eat or drink immediately after taking an oral film?
This depends on the specific medicine. For many oral films, it is recommended to avoid eating or drinking until the film has completely dissolved. Some products may require waiting a few additional minutes to ensure optimal absorption. Always follow the instructions provided in the patient information leaflet.

4. How should unused oral films be stored?
Keep them in their original packaging, at room temperature, away from light and moisture, and out of reach from children and pets. This helps preserve their integrity and effectiveness. Do not open the individual sachet until you are ready to use the film.

5. Can I cut or split an oral film to adjust the dose?
Unless the manufacturer specifically states that the film can be divided, oral films should not be cut or split. Doing so may result in an inaccurate dose or affect the medicine's performance. If a different dose is required, your healthcare professional can prescribe a more appropriate strength, if available. Always follow the instructions provided in the patient information leaflet.

6. What should I do if the film breaks before I use it?
If the film is damaged, torn, or broken before administration, it should generally not be used unless the manufacturer specifically indicates otherwise. Use a new oral film to ensure the correct dose is administered.

7. Can I use an oral film after its expiration date?
It is important not to use an oral film after the expiration date indicated on its packaging. Beyond this date, the medicine may no longer deliver the expected therapeutic effect, as the stability of the active pharmaceutical ingredient and the integrity of the film can no longer be guaranteed. In addition, the physical characteristics of the film, such as its flexibility, dissolution time, or overall performance, may be altered by storage over time. To ensure safe and effective treatment, always use an oral film that is within its expiration date and has been stored according to the manufacturer's recommendations.

8. Can I take more than one oral film or use it with other medicines?
Only use the number of oral films prescribed by your healthcare professional or indicated in the patient information leaflet. Taking more films than recommended may increase the risk of side effects or overdose. Likewise, oral films may interact with prescription medicines, over-the-counter drugs, herbal products, or dietary supplements. To minimize these risks, inform your doctor and pharmacist about all the medicines and supplements you are taking. They can assess potential interactions and advise you on any necessary precautions.

9. What should I do if I miss a dose?
The appropriate action depends on the medicine contained in the oral film. Always check the instructions provided in the package leaflet. Depending on the product, you may be advised to take the film as soon as you remember or to wait until the next scheduled dose. Do not take two films at the same time to make up for a missed dose, unless specifically instructed by your doctor. If you are unsure, ask your doctor or pharmacist for advice.

10. What should I do if I experience side effects?
If you notice a side effect not mentioned in the patient information leaflet or experience a serious reaction, consult your doctor or pharmacist. They can evaluate the situation and recommend the most appropriate course of action. Remember that any suspected adverse reaction can also be reported directly by patients or patient associations to regional pharmacovigilance centers.

When in doubt

Never hesitate to consult your pharmacist or doctor if you have any questions or concerns about using an oral film. Their expertise can help ensure that your treatment is both safe and effective.